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Sunday, August 9, 2026

The Mind-Boggling Odds Against Random Protein Evolution

In this interview segment, Dr. Stephen Meyer interviews author and mathematician Dr. David Berlinski, exploring the mathematical and combinatorial challenges to neo-Darwinian evolutionary theory. Tracing the history back to Wistar Institute discussions with Murray Eden, Berlinski explains how the vast combinatorial space of protein sequences makes random search mechanisms statistically incapable of discovering functional biological targets. The conversation also details the concept of digital information sequences having vastly more ways to fail than succeed, as well as the lasting cultural and scientific impact of Berlinski's famous 1996 essay, "The Deniable Darwin."

Speaker and Guest: Stephen Meyer, David Berlinski

 

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